Bioactivity | (E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol (HY-14616), is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells[1][2]. | ||||||||||||
Invitro | (E)-[6]-Dehydroparadol (M15) (5-80 µM; 24 h) inhibits the growth of HCT-116 and H-1299 cells, with IC50s of 43.02 and 41.59 µM, respectively[1].(E)-[6]-Dehydroparadol (10-40 µM; 24 h) induces apoptosis in HCT-116 and H-1299 cells[1]. | ||||||||||||
Name | (E)-[6]-Dehydroparadol | ||||||||||||
CAS | 878006-06-5 | ||||||||||||
Formula | C17H24O3 | ||||||||||||
Molar Mass | 276.37 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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